β-硅酸二钙骨水泥的水化改性及其生物活性的研究The Hydration Modification and Bioactivity of Beta-dicalcium Silicate Bone Cements
谢洪海;王玉清;
摘要(Abstract):
成功地合成了含球霰石β-硅酸二钙生物骨水泥,目的是为了降低β-硅酸二钙骨水泥水化产物Ca(OH)_2的碱性对生物材料的不利影响,并提高β-硅酸二钙骨水泥的生物活性。将含球霰石与不含球霰石的β-硅酸二钙骨水泥浸泡到人体模拟液(SBF)中3天,使用XRD、SEM、EDS和FT-IR对其表面形成的羟基磷灰石进行分析与研究,发现含球霰石的β-硅酸二钙骨水泥的体外生物活性明显提高了;对水化改性后的β-硅酸二钙的凝结时间也进行了评价。结果表明,含球霰石的β-硅酸二钙骨水泥的羟基磷灰石形成能力更好,凝结时间(12±2 min)适合于临床操作的使用,是极具应用前景的骨修复替代材料。
关键词(KeyWords): β-硅酸二钙;水化;球霰石;生物活性
基金项目(Foundation):
作者(Authors): 谢洪海;王玉清;
DOI: 10.13958/j.cnki.ztcg.2019.03.001
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